Arabidopsis Interactome
-1
In collaboration with Center for Cancer Systems Biology, 9000
Arabidopsis protein-coding genes were systematically screened in a
high-quality, matrix-based Y2H assay. Proteins were tested for binary
interactions against one another (AI-1) as well as against Arabidopsis pathogen
effector proteins (PPIN-1).
The AI-1
network contains 6205 protein-protein interactions among 2,774 Arabidopsis
proteins. It was generated as detailed in "Evidence for Network Evolution in an
Arabidopsis Interactome Map" Science July 29, 2011. Click to search genes of interest and browse
the AI-1 network.
The PPIN-1 network contains 3148 protein-protein interactions among 926
Arabidopsis immune related proteins. Please see "Independently Evolved
Virulence Effectors Converge onto Hubs in a Plant Immune System Network" Science July 29, 2011, for details. Click to search genes of interest
and browse the PPIN-1 network. Click here to download PPIN-1 dataset.
The NAPPA network: The 38 transcription factors resulted in a protein-protein interaction network containing 3,577 interactions and 2,238 proteins. download NAPPA dataset.
Visit
the CCSB Arabidopsis Interactome webpage at
http://interactome.dfci.harvard.edu/A_thaliana/index.php?page=home
http://interactome.dfci.harvard.edu/A_thaliana/index.php?page=display
Funding provided by the National Science Foundation